Trigeminal Trophic Syndrome – Case Report

  • Boštjan Matos University clinical center Ljubljana
  • Neža Prezelj Medical faculty Ljubljana
Keywords: trigeminal trophic syndrome, statoacoustic neuroma, facial ulceration, wound healing, facial flap surgery


Trigeminal trophic syndrome is a rare condition resulting from compulsive self-manipulation of the skin after a peripheral or central injury to the trigeminal system. The classic triad consists of trigeminal anesthesia, facial paresthesias, and crescentric lateral nasal alar erosion and ulceration. Although the symptoms are visibly clear, the diagnosis is not easy to establish. The appearance of the ulcers mimics many other disease entities such as neoplasm, infection, granulomatous disease, vasculitis and factitial dermatitis. Trigeminal trophic syndrome should be considered with a positive neurologic history and when laboratory and biopsy workup is inconclusive. Once diagnosis is confirmed, treatment is complicated and often multidisciplinary. We report a case of a woman who developed a strictly unilateral crescent ulcer of the ala nasi after resection of an statoacoustic neurinoma. A clinician who is faced with a patient with nasal ulceration should consider this diagnosis.






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Author Biography

Boštjan Matos, University clinical center Ljubljana
department of neurosurgery


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How to Cite
Matos B, Prezelj N. Trigeminal Trophic Syndrome – Case Report. ZdravVestn [Internet]. 29May2015 [cited 22Sep.2019];84(4). Available from:
Case report, short scientific article