ETIOLOGICAL FACTORS FOR VOCAL FOLD POLYP FORMATION

  • DAŠA GLUVAJIĆ Klinika za otorinolaringologijo in cervikofacialno kirurgijo, Univerzitetni klinični center Ljubljana, Zaloška cesta 2, Ljubljana
  • IRENA HOČEVAR BOLTEŽAR Klinika za otorinolaringologijo in cervikofacialno kirurgijo, Univerzitetni klinični center Ljubljana, Zaloška cesta 2, Ljubljana
Keywords: vocal fold, polyp, hoarsness, smoking, gastroesophageal reflux, voice load

Abstract

Background: Vocal fold polyp is one of the most common causes for hoarseness. Many different etiological factors contribute to vocal fold polyp formation. The aim of the study was to find out whether the etiological factors for polyp formation have changed in the last 30 years.

Methods: Eighty-one patients with unilateral vocal fold polyp were included in the study. A control group was composed of 50 volunteers without voice problems who matched the patients by age and gender. The data about etiological factors and the findings of phoniatric examination were obtained from the patients' medical documentation and from the questionnaires for the control group. The incidence of etiological factors was compared between the two groups. The program SPSS, Version 18 was used for statistical analysis.

Results: The most frequent etiological factors were occupational voice load, GER, allergy and smoking. In 79% of patients 2 – 6 contemporary acting risk factors were found. Occupational voice load (p=0,018) and GER (p=0,004) were significantly more frequent in the patients than in the controls. The other factors did not significantly influence the polyp formation.

Conclusions: There are several factors involved simultaneously in the formation of vocal fold polyps both nowadays and 30 years ago. Some of the most common factors remain the same (voice load, smoking), others are new (GER, allergy), which is probably due to the different lifestyle and working conditions than 30 years ago. Occupational voice load and GER were significantly more frequently present in the patients with polyp than in the control group. Regarding the given results it is important to instruct workers with professional vocal load about etiological factors for vocal fold polyp formation.

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References

Kambič V. Otorinolaringologija. Ljubljana: Mladinska knjiga; 1984.

Uloza V. Atlas of laryngeal diseases. Vilnius: Mokslas; 1986. p. 55-64.

Kleinsasser O. Microlaryngoscopy and endolaryngeal microsurgery. 3rd ed. Stuttgart-New York: Schattauer; 1991. p. 34-8.

Lehman W, Pidoux JM, Widmann JJ. Larynx: microlaryngoscopy and histopathology. Cadempino: Impharzam SA; 1981. p. 68.

Tucker HM. The larynx. 2nd ed. New York: Thieme Medical Publishers; 1993. p. 40-3.

Zeitels SM. Atlas of phonomicrosurgery and other endolaryngeal procedures for benign and malignant disease. Delmar: Singulair; 2001. p. 37.

Mathieson L. Greene and Mathieson’s The voice and its disorders. 6th ed. London and Philadelphia: Whurr Publishers; 2001.

Kambič V, Radšel Z, Žargi M, et al. Vocal cord polyps: incidence, hystology and pathogenesis. J Laryngol Otol 1981; 95: 609-18.

Kleinsasser O. Pathogenesis of vocal cord polyps. Ann Otol Rhinol Laryngol 1982; 91: 378-81.

Barnes L. Diseases of the larynx, hypopharynx, and trachea. In: Barnes L, ed. Surgical pathology of the head and neck. 3rd ed. Vol. 1. New York: Informa Healthcare; 2009. p. 109-200.

Kumar V, Abul KA, Nelson F, et al., eds. Robbins and Cotran pathologic basis of disease. 8th ed. Philadelphia: Saunders Elsevier; 2010. p. 43-77.

Hammond TH, Zhou R, Hammond EH, et al. The intermediate layer: a morphologic study of the elastin and hyalurinic acid constituents of normal vocal folds. J Voice 1997; 11: 59-66.

Thibeault SL, Gray SD, Li W, et al. Genotypic and phenotypic expression of vocal fold polyps and Reinke's edema: a preliminary study. Ann Otol Rhinol Laryngol 2002; 111: 302-9.

Vilkman E. Voice problems at work: a challenge for occupational safety and health arrangement. Folia Phoniatr Logop 2000; 52: 120-5.

Child DR, Johnson TS. Preventable and nonpreventable causes of voice disorders. Semin Speech Lang 1991; 12: 1-12.

Sataloff RT, Spiegel JR. Care of professional voice. Otolaryngol Clin North Am 1991; 24: 1093-124.

Spiegel JR, Hawkshaw M, Sataloff RT. Dysphonia related to medical therapy. Otolaryngol Clin North Am 2000; 33: 771-84.

Hočevar Boltežar I. Fiziologija in patologija glasu ter izbrana poglavja iz patologije govora. Ljubljana: Pedagoška fakulteta Univerze v Ljubljani; 2008.

Dixon HS. Allergy and laryngeal disease. Otoryngol Clin North Am 1992; 25: 239-50.

Tietze IR. Principles of voice production. Engelwood Cliffs, NJ: Prentice Hall; 1994. p. 307-29.

Laguaite JK. Adult voice screening. J Speech Hear Disord 1972; 37: 147-51.

Eckley CA, Swensson J, Duprat Ade C, et al. Incidence of structural vocal fold abnormalities associated with vocal fold polyps. Braz J Otorhinolyngol 2008; 74 (4): 508-11.

Remacle M. The contribution of videostroboscopy in daily ENT practice. Acta Otorhinolaryngol Belg 1996; 50: 265-81.

Gray SD, Pignatari SN, Harding P. Morphologic ultrastructure of anchoring fibers in normal vocal fold basement membrane zone. J Voice 1994; 8: 48-52.

Pleterski G, Ivanuša M, Drinovec J, et al. Epidemiološka ocena pogostnosti gastroezofagealne refluksne bolezni za Slovenijo. Zdrav Vestn 2002; 71: 379-84.

Tutuian R, Castell DO. Diagnosis of laryngopharyngeal reflux. Curr Opin Otoryngol Head Neck Surg 2004; 12: 174-9.

Wiener GJ, Koufman JA, Wu WC, Cooper JB, Richter JE, Castell DO. Chronic hoarseness secondary to gastroesophageal reflux disease: documentation with 24-h ambulatory pH monitoring. Am J Gastroenterol 1989; 84(12): 1503-8.

Roth D, Ferguson BJ. Vocal allergy: recent advances in understanding the role of allergy in dysphonia. Curr Opin Otolaryngol Head Neck Surg 2010; 18: 176-81.

Hočevar-Boltežar I, Radšel Z, Žargi M. The role of allergy in the etiopathogenesis of laryngeal mucosal lesions. Acta Otoryngol (Stockh) 1997; 527 (Suppl): 134-7.

Gnjatić M, Stanković P, Đukić V. Uticaj pušenja i zloupotrebe glasa na pojavu polipa na glasnicama. Acta Chir Iugosl 2009; 56 (2): 27-32.

Koprivnikar H. Izpostavljenost tobačnemu dimu in kadilske navade polnoletne populacije RS v letih 2006 in 2008. Zbornik povzetkov ob Svetovnem dnevu brez tobaka 2008. Ljubljana: Inštitut za varovanje zdravja RS, 2008.

Kravos A, Hočevar Boltežar I. Reinkejev edem glasilk. Zdrav Vestn 2010; 79: 853-60.

Uradni list RS, št. 56/99, 64/01 in 43/11 – ZVZD-1. Dosegljivo s spletne strani .

Kravos A, Župevc A, Čizmarević B, et al. The role of allergy in the etiology of Reinke's edema on vocal folds. Wien Klin Wochenschr 2010; 122 (Suppl 2): 44-8.

Published
2016-05-07
How to Cite
1.
GLUVAJIĆ D, HOČEVAR BOLTEŽAR I. ETIOLOGICAL FACTORS FOR VOCAL FOLD POLYP FORMATION. ZdravVestn [Internet]. 7May2016 [cited 22Nov.2019];85(3). Available from: https://vestnik.szd.si/index.php/ZdravVest/article/view/1403
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Original article