Background. The pancreatic cancer is quite common malignant tumor of gastointestinal tract and its incidence is increasing in well developed part of the world. Despite of all advanced diagnostic methods the disease is in most cases recognised too late when the tumor is not resectable.
Conclusions. Only in 20–30% of patients with pancreatic cancer surgical resection is possible, and even in this group 5year survival is very low. In the patients where the tumor is not resectable, sometimes only palliative procedures are indicated and sometimes only simptomatic therapy is possible. The average survival period in this group of patients is 12–20 months. Adjuvant chemo and radiotherapy has not shown much of benefit and the prognosis is still very bad.
Rosewicz S, Wiedenmann B. Pancreatic carcinoma. Lancet 1997; 349: 485– 9.
Tsuchiya R, Harada N, Tsunoda T, Miyamoto T, Ura K. Long-term survivors after operation on carcinoma of the pancreas. Int J Pancreatol 1988; 3: 491– 6.
Schnall SF, Macdonald JS. Chemotherapy of adenocarcinoma of the pancreas. Semin Oncol 1996; 23: 220–8.
Pedrazzoli S, Pasquali C, Sperti C. General aspects of surgical treatment of pancreatic cancer. Dig Surg 1999; 16: 265–75.
Choi BI, Chung MJ, Han JK. Detection of pancreatic adenocarcinoma: Relative value of arterial and late phases of spiral CT. Abdom Imaging 1997; 22: 199–203.
Warshaw AL, Gu ZY, Wittenberg J, Waltman AC. Preoperative staging and assessment of resectability of pancreatic cancer. Arch Surg 1990; 125: 230– 3.
Ichikawa T, Haradome H, Hachiya J. Pancreatic ductal adenocarcinoma: preoperative assessment with helical CT versus dynamic gadolinium MR imaging. Radiology 1997; 202: 655–62.
Diehl SJ, Lehmann KJ, Sadick M, Lackmann R, Georgi M. Pancreatic cancer: Value of dual-phase helical CT in assessing resectability. Radiology 1998; 206: 373–8.
Wiersema MJ. Accuracy of endoscopic ultrasound in diagnosing and staging pancreatic carcinoma. Pancreatology 2001; 1: 610–24.
Freeny PC. The contribution of diagnostic imaging for the general surgeon. Prob Gen Surg 1997; 14: 3–12.
Andren-Sandberg A, Hoem D, Gislason H. Aspects of radical surgery for exocrine cancer of the pancreatic head: In: Lankisch PG, DiMagno EP eds. Pancreatic disease. State of the art and future aspects of research. Berlin/ Heidelberg: Springer-Verlag, 1999: 238–49.
Friess H, Uhl W, Berger HG, Büchler MW. Surgical treatment of pancreatic cancer. Dig Surg 1994; 11: 378–86.
Trede M, Saeger HD, Schwall G, Rumstadt B. Resection of pancreatic cancer – surgical achievements. Langenbecks Arch Surg 1998; 383: 121–8.
Balcol JH, Rattner DW, Warshaw AL, Chang Y, Fernandez del Castillo C. Ten year experience with 733 pancreatic resections. Changing indications, older patients and decreasing lenght of hospitalization. Arch Surg 2001; 136: 391–8.
Gouma DJ, de Wit LT, van Berge Henegouwen MI, van Gulik TM, Obertop H. Rates of complications and death after pancreaticoduodenectomy: Risk factors and impact of hospital volume. Ann Surg 2000; 232: 786–95.
Neoptolomeos JP, Dunn JA, Moffitt DD, Almond J et al. Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: A randomised controlled trial. Lancet 2001; 358: 1576–85.
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