THE EFFECT OF EARLY CERVICAL CANCER DIAGNOSIS

  • Herman Haller Department of Obstetrics and Gynecology, Clinical Hospital Centre of Rijeka, University of Rijeka, Cambierieva 17/5, 51000 Rijeka
  • Maja Krašević Department of Pathology, School of Medicine Rijeka, University of Rijeka, Cambierieva 13, 51000 Rijeka
  • Ozren Mamula Department of Obstetrics and Gynecology, Clinical Hospital Centre of Rijeka, University of Rijeka, Cambierieva 17/5, 51000 Rijeka
  • Danko Perović Department of Obstetrics and Gynecology, Clinical Hospital Centre of Rijeka, University of Rijeka, Cambierieva 17/5, 51000 Rijeka
  • Alenka Brnčić-Fischer Department of Obstetrics and Gynecology, Clinical Hospital Centre of Rijeka, University of Rijeka, Cambierieva 17/5, 51000 Rijeka
  • Senija Eminović Department of Pathology, School of Medicine Rijeka, University of Rijeka, Cambierieva 13, 51000 Rijeka
  • Danijela Vrdoljak-Mozetič Division of gynecologic cytology, Department of Obstetrics and Gynecology, Clinical Hospital centre of Rijeka, University of Rijeka, Cambierieva 17/5, 51000 Rijeka
  • Miroslav Stamatović Department of Obstetrics and Gynecology, Clinical Hospital Centre of Rijeka, University of Rijeka, Cambierieva 17/5, 51000 Rijeka
  • Miljenko Manestar Department of Obstetrics and Gynecology, Clinical Hospital Centre of Rijeka, University of Rijeka, Cambierieva 17/5, 51000 Rijeka
Keywords: cervical cancer, conization, hysterectomy, FIGO, radical hysterectomy

Abstract

Background: Treatment effectiveness and clinical outcome of patients with cervical carcinoma FIGO stage IA1 and IA2 are analyzed in three different time period at the Department of Obstetrics and Gynecology Rijeka, Croatia.

Method: Retrospective analysis of the hospital chart of all cervical cancer patients between 1991 and 2005 was conducted with five-year follow up.

Results: Data on cervical cancer distribution by stage and five-year survival are presented. Separately analyzed age, histology type and treatment modalities in stage FIGO IA1 and IA2 during three consecutive five-year periods are presented.

Conclusions: Conservative surgical approach – conization alone in stage IA1 of the squamous cell car- cinoma is reasonable and safe treatment option for reproductive active women. During observed periods conization became the most used surgical technique applied in almost two third of FIGO IA1 cervical cancer patients. Lymph vascular space invasion in stage IA1 lead to adjunct pelvic lymphadenectomy with unclear clinical benefit. In cervical cancer patients stage IA2 simple hysterectomy and pelvic lymphadenectomy could be accepted as a standard treatment. In these patients further studies are recommended to evaluate other less radical surgical techniques – simple and radical trachelectomy with or without pelvic lymphadenectomy. Radical hysterectomy in both stages IA1 and IA2, based on personal experience and literature data represents a surgical overtreatment and should be abandoned.

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Published
2018-02-14
How to Cite
1.
Haller H, KraševićM, Mamula O, PerovićD, Brnčić-FischerA, EminovićS, Vrdoljak-MozetičD, StamatovićM, Manestar M. THE EFFECT OF EARLY CERVICAL CANCER DIAGNOSIS. ZdravVestn [Internet]. 14Feb.2018 [cited 27May2019];78. Available from: https://vestnik.szd.si/index.php/ZdravVest/article/view/2731
Section
Review