Cancer chemotherapy and cognitive dysfunction

  • Blanka Kores Plesničar
  • Andrej Plesničar


Background: Cancer chemotherapy is associated with numerous side effects, one of them being cognitive impairment, which is poorly known and insufficiently recognised in clinical practice. Memory, concentration, attention, and executive function deficits are associated with chemotherapy, hormone therapy, and also with treatments using biological response modifiers. Cognitive disorders may be either mild or more severely pronounced, and they often prevent the patients to return to their previous level of functioning. Symptomatic treatment of these disorders is still limited; cognitive and behaviour strategies may prove beneficial, together with positive reinforcement and education. Conclusions: Cancer treatment is becoming more and more effective; therefore, quality of life and the ability to return effectively to everyday life is ever more important. Recognition of cognitive sequelae of cancer treatment and their management will thus be included in the multidisciplinary treatment of cancer patients in the future.


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How to Cite
Kores Plesničar B, Plesničar A. Cancer chemotherapy and cognitive dysfunction. ZdravVestn [Internet]. 1Sep.2012 [cited 7Apr.2020];81(9). Available from: