Intracranial haemorrhage in a neonate with severe haemophilia A: A case report and literature review
AbstractBackground: Intracranial haemorrhage (ICH) is a serious complication of haemophilia that affects 3.5–4 % of all boys with haemophilia during the neonatal period. It is a leading cause of mortality and morbidity in neonates with haemophilia. Patients and Methods: The authors are presenting a case of a neonate with severe haemophilia A, who suffered postnatal ICH. They discuss dilemmas regarding the optimal mode and management of delivery in haemophilia carriers, the role of imaging techniques in diagnosing ICH and postpartum prophylaxis. Authors also discuss the choice of factor concentrate for the treatment of ICH and present the data on perinatal complications in neonates with severe haemophilia A in Slovenia in the period 1980–2010. Conclusions: ICH is a leading cause of mortality and morbidity in neonates with coagulation disorders. Early recognition of ICH and early appropriate management are extremely important.
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