Vernix caseosa peritonitis – A case report and review of the literature
DOI:
https://doi.org/10.6016/ZdravVestn.3397Keywords:
vernix caseosa, peritonitis, case report, cesarean section, postoperative complicationAbstract
Vernix caseosa peritonitis is a rare complication following caesarean section or, less commonly, vaginal delivery, presenting as a hyperinflammatory reaction following the leakage of vernix- or meconium- containing amniotic fluid into the woman’s abdomen. The clinical picture shows an acute abdomen associated with high inflammatory parameters a few days after delivery. The pathophysiological mechanism of the inflammatory process is not fully understood. In our article, we present the case of a 22-year-old woman who had diffuse peritonitis with a turbulent inflammatory reaction on the fifth day after a caesarean section in the 40th week of pregnancy. There are only 30 such case reports in the world literature; to our knowledge, this is the first in Slovenia.
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1. Nishijima K, Yoneda M, Hirai T, Takakuwa K, Enomoto T. Biology of the vernix caseosa: a review. J Obstet Gynaecol Res. 2019;45(11):2145-9.
DOI: 10.1111/jog.14103
PMID: 31507021
2. Danawar NA, ALmosalami IA, El Amine Elhadj O, Anis R, Bubshait A. Vernix Caseosa Peritonitis as a Rare Cause of Acute Abdomen After Cesarean Section. Cureus. 2021;13(9):e17953.
DOI: 10.7759/cureus.17953
PMID: 34660141
3. Tawfik O, Prather J, Bhatia P, Woodroof J, Gunter J, Webb P. Vernix caseosa peritonitis as a rare complication of cesarean section. A case report. J Reprod Med. 1998;43(6):547-50.
PMID: 9653703
4. Selo-Ojeme D. Vernix caseosa peritonitis. J Obstet Gynaecol. 2007;27(7):660-3.
DOI: 10.1080/01443610701582792
PMID: 17999288
5. Sadath SA, Abo Diba FI, Nayak S, Shamali IA, Diejomaoh MF. Vernix caseosa peritonitis after vaginal delivery. Clin Med Insights Case Rep. 2013;6:147-52.
DOI: 10.4137/CCRep.S12771
PMID: 24151427
6. Cathelain A, Helbert P, Petit S, Fromentin C, Valat AS. Vernix caseosa peritonitis after vaginal delivery: A rare and unrecognized postpartum complication. Gynecol Obstet Fertil Senol. 2019;47(11):819-21.
DOI: 10.1016/j.gofs.2019.06.005
PMID: 31229675
7. Val-Bernal JF, Mayorga M, García-Arranz P, Salcedo W, León A, Fernández FA. Vernix caseosa peritonitis: report of two cases. Turk Patoloji Derg. 2015;31(1):51-5.
DOI: 10.5146/tjpath.2014.01275
PMID: 25110245
8. Myers JR, Fernando C. Radiology of vernix caseosa peritonitis: case report and discussion. J Med Imaging Radiat Oncol. 2011;55(3):301-3.
DOI: 10.1111/j.1754-9485.2011.02271.x
PMID: 21696565
9. Becker-Weidman D, Chung CM, Nadeem M, Virk J, Chung C. Computed Tomography Findings in Vernix Caseosa Peritonitis. J Comput Assist Tomogr. 2020;44(5):780-3.
DOI: 10.1097/RCT.0000000000001079
PMID: 32842059
10. Bailey JG, Klassen D. Laparoscopic experience with vernix caseosa peritonitis. Surg Endosc. 2012;26(11):3317-9.
DOI: 10.1007/s00464-012-2320-6
PMID: 23052489
11. Yang CH, Eykman EN, Smith CJ, Bacon J, Morris JM, Baber RJ, et al. Vernix caseosa peritonitis causing acute abdomen after cesarean section: A case series. Am J Case Rep. 2023;24:e938276.
DOI: 10.12659/ajcr.938276
DOI: 10.12659/AJCR.938276
PMID: 36604865
12. Mihajlović D, Đoković N, Vitković L, Šulović N, Mijović M. Preterm Prelabour Rupture of Membranes and Vernix Caseosa Peritonitis: A Case Report. Acta Facultatis Mdicae Naissensis. 2022;39(1):106-12.
DOI: 10.5937/afmnai39-31021
PMID: 19208257
13. Stuart OA, Morris AR, Baber RJ. Vernix caseosa peritonitis - no longer rare or innocent: a case series. J Med Case Rep. 2009;3(1):60.
DOI: 10.1186/1752-1947-3-60
PMID: 19208257
14. Mahmoud A, Silapaswan S, Lin K, Penney D. Vernix caseosa: an unusual cause of post-cesarean section peritonitis. Am Surg. 1997;63(5):382-5.
PMID: 9128220
15. Chambers AC, Patil AV, Alves R, Hopkins JC, Armstrong J, Lawrence RN. Delayed presentation of vernix caseosa peritonitis. Ann R Coll Surg Engl. 2012;94(8):548-51.
DOI: 10.1308/003588412X13373405385296
PMID: 23131223
16. Davis JR, Miller HS, Feng JD. Vernix caseosa peritonitis: report of two cases with antenatal onset. Am J Clin Pathol. 1998;109(3):320-3.
DOI: 10.1093/ajcp/109.3.320
PMID: 9495205
17. Vieillefosse S, De Laveaucoupet J, Cohen M, Prevost S, Dufau JP, Benachi A, et al. A case study of vernix caseosa peritonitis. J Gynecol Obstet Hum Reprod. 2018;47(9):491-3.
DOI: 10.1016/j.jogoh.2018.08.012
PMID: 30144557
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