Guidelines for antibiotic prophylaxis in abdominal surgery for adults

  • Tadeja Pintar UKC Ljubljana
  • Blaž Trotovšek UKC Ljubljana, KO za abdominalno kirurgijo
  • Bojana Beović Klinika za infekcijske bolezni in vročinska stanja, UKC Ljubljana
Keywords: antibiotic prophylaxis, abdominal surgery, guidlines.

Abstract

Abstract: Background.Evidence based recommendations for antibiotic prophylaxis in abdominal surgery are prepared to reduce postoperative complications and to reduce inappropriate prophylactic antibiotic prescribing. The original guidline address risk factors for surgical site infection (SSI), benefits and risks of antibiotic profilaxis and  indications for surgical antibiotic profilaxis.

Update of recommendations is an opportunity to expand and review the evidence supporting recommendations. Recommendations for common surgical procedures in abdominal surgery in adults are included in this guideline.

Surgical antibiotic prophylaxis is and adjunct to, not a substitue for, good surgical tecnique. Antibiotic prophylactic should be regarded as one component of an effective policy for the control of healthcare-associated infection.

 

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References

Literatura.

Harbour R, Miller J. A new system for grading recommendations in evidence-based clinical guidelines. BMJ 2001; 323: 334-6.

SIGN Guidelines, Published July 2008, revision June 2013. Dosegljivo 27.3.2014 na: http://www.sign.ac.uk/guidelines/published/numlist.html.

Surgery Specific Quick Reference Guidelines. Dosegljivo 27.3.2014 na: http://www.sign.ac.uk/guidelines/fulltext/104/qrgs.html.

Bratzler DW, Dellinger EP, Olsen KM, Perl TM, Auwaerter PG, Bolon MK, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health-Syst Pharm. 2013; 70:195-283.

Gross A. Surgical Prophilaxis revisied 7.12. The Nebraska Medical Center. Jan.2013.

Guidelines for Antimicrobial Usage 2008-2009 Tables 29 - 31 from the Cleveland

Clinic.

Delovna skupina C13. Slovenski priročnik za smernice 2003. Dostopno na: www.mz.gov.si/si/delovna_podrocja/zdravstveno_varstvo/kakovost_in_varnost_sistema_zdravstvenega_varstva/klinicne_smernice/

Čižman M, Beović B. Kako predpisujemo protimikrobna zdravila v bolnišnicah Ljubljana: Sekcija za protimikrobno zdravljenje Slovenskega zdravniškega društva; 2013.

National Collaborating Centre for Women’s and Children’s Health. Comissioned by the Ntional institute for health and Clinical excellence. Surgical site infection prevention and treatment of surgical site infection. RCOG Press 2008 London.

Štrumbelj I, Berce I, Čretnik-Žohar T, Harlander T, Jeverica S, Kavčič M, et al. Pregled občutljivosti baketrij za antibiotike –Slovenija 2012. 1. izd. Ljubljana: Slovenska komisija za ugotavljanje občutljivosti za protimikrobna zdravila (SKUOPZ); 2013. Dosegljivo na: http://www.imi.si/strokovna-zdruzenja/skuopz).

Anon. SNLG - Antibioticoprofilassi perioperatoria nell’adulto. Dostopno na www.snlg-iss.it.

Francetić I, Sardelić S, Bukovski-Simonoski S, Santini M, Betica-Rdij L, Belina D, el al. Smjernice ISKRA za antimikrobnu profilaksu u kirurgiji – hrvatske nacionalne smjrnice. Liječ Vjesn 2010; 32: 203-17.

Classens DC, Ewans RS, Pestotnik SL, Horn SD, Menlove RL, Burke JP. The timimg of prophylactic administration of antibiotic prophylaxis and the risk of surgical wound infection N Engl J Med 1992; 326: 281-6.

Steinberg JP1, Braun BI, Hellinger WC, Kusek L, Bozikis MR, Bush AJ et al; Trial to reduce antimicrobial prophylaxis errors (TRAPE) Study Group. Timing of antimicrobial prophylaxis and the risk of surgical site infections: results from the Trial to Reduce Antimicrobial Prophylaxis Errors. Ann Surg. 2009;250:10-16.

Weber WP1, Marti WR, Zwahlen M, Misteli H, Rosenthal R, Reck S et al. The timing of surgical antimicrobial prophylaxis. Ann Surg. 2008;247:918-926.

Hawn MT, Richman JS, Vick CC, Deierhoi RJ, Graham LA, Henderson WG, Ita KMFni. Timing of surgical antibiotic prophylaxis and the risk of surgical site infection. JAMA Surg 2013;148: 649-57.

Morris DL, Yound D, Burdon DW, Keighley MR.Prospective randomized trial of singledose cefuroxime against mezlocillin in elective gastric surgery. J Hosp Infect. 1984; 5:200-4.

Suehiro T, Hirashita T, Arki S, Matsumata T, Tsutsumi S, Mochiki E, et al. Prolonged antibiotic prophylaxis longer than 24 hours does not decrease surgical site infections after elective gastric and coloractal surger. Hepatogastroenterology 2005; 55:1636-9.

Wang F, Chen XZ, Liu J, Yang K, Zhang B, Chen ZX. Short-term versus long-term administration of single prophylactic antibiotic in elective gastric tumor surgery. Hepatogastroenterology. 2012; 59:1784-8.

Imamura H, Kurokawa Y, Tsujinaka T, Inoue K, Kimura Y, Iijima S. Intraoperative versus extended antimicrobial prophylaxis after gastric cancer surgery: a phase 3, open-label, randomised controlled, non-inferiority trial.

Van Kasteren MEE, Gyssens IC, Kullberg BJ, Bruining HA, Stobberingh, Goris RJA. Optimaliseren van het antibioticabeleid in Nederland. V. SWAB-richtlijnen voor perioperatieve antibiotische profylaxe. Ned Tijdschr Geneeskd 2000; 144: 2049-55.

Wacha A, Hoyme U, Isenmann R, Kujath P, Lebert C, Naber K, Salzberger B. Perioperative Antibiotika Prophylaxe. Chemother J 2010; 19: 70-84.

National Collaborating Centre for Women’s and Children’s Health. Comissioned by the Ntional institute for health and Clinical excellence. Surgical site infection prevention and treatment of surgical site infection. RCOG Press 2008 London.

Meijer WS, Smitz PI, Jeekel J.Meta-analysis of randomized, controlled clinical trials of antibiotic prophylaxis in biliary tract surgery. Br J Surg. 1990;77:283-90.

Lippert H, Gastinger J. Antimicrobial prophylaxis in laparoscopic an conventional cholecystectomy. Chemotherapy 1998; 44:355-63.

Choudhary A, Bechthold ML, Puli SR, Othman MO, Roy PK. Role of prophylactic antibiotics in laparoscopic cholecystectomy: A meta-analysis. J Gastrointest Surg 2008; 12:1847–1853.

Catarci M, Mancini S, Gentileschi P, camplone P, Sileri GB. Antibiotic prophylaxis in elective laparoscopic cholecystectomy Lack of need or lack of evidence? Surg Endosc 2004; 18: 638–64.

Uludag M, Yetkin G, Citgez B. The Role of Prophylactic antibiotics in elective laparoscopic cholecystectomy. JSLS 2009; 13:337–341.

Sanabria A, Dominguez LC, Valdivieso E, Gomez G. Antibiotic prophylaxis for patients undergoing elective laparoscopic cholecystectomy. Cochrane Database of Systematic Reviews 2010, Issue 12. Art. No.: CD005265.

Song F, Glenny AM. Antimicrobial prophylaxis in colorectal surgery: a systematic review of randomised controlled trials. Health Technol Assessment 1998; 7: 1-110.

Suehiro T, Hirashita T, Arki S, Matsumata T, Tsutsumi S, Mochiki E et al. Prolonged antibiotic prophylaxis longer than 24 hours does not decrease surgical site infections after elective gastric and coloractal surger. Hepatogastroenterology 2005; 55:1636-9.

Suzuki T, Sadahiro S, Maeda Y, Tanaka A, Okada K, Kamijo A. Optimal duration of prophylactic antibiotic administration for elective colon cancer surgery. Surgery 2011:149:171-8.

Council of the European Union. Council conclusions on the impact of antimicrobial resistance in the human health sector and in the veterinary sector – a “One Health” perspective. Dostopno na: http://www.consilium.europa.eu/uedocs/cms_data/docs/pressdata/en/lsa/131126.pdf).

Lewis RT. Oral versus systemic antibiotic prophylaxis in elective colon surgery: a randomized study and meta-analysis send a message from the 1990s. Can J Surg 2002; 45:173-80.

Fry DE. Preventive systemic antibiotics in colorectal surgery. Surg Infect 2008; 9:547-552.

Toneva GD, Deierhoi RJ, Morris M, Richman J, Cannon JA, Altom LK, et al. Oral antibiotic bowel preparation reduces length of stay and readmissions after colorectal surgery. J Am Coll Surg 2013; 216:756-63.

Kobayashi M , Yasuhiko Mohri Y, Tonouchi H, Miki C2 Nakai K, Masato Kusunoki M, on behalf of the Mie Surgical Infection Research Group. Randomized clinical trial comparing intravenous antimicrobial prophylaxis alone with oral and intravenous antimicrobial prophylaxis for the prevention of a surgical site infection in colorectal cancer surgery. Surg Today 2007; 37:383-8.

Dale W. Bratzler, E. Patchen Dellinger, Keith M. Olsen, Trish M. Perl, Paul G. Auwaerter, Maureen K. Bolon, Douglas N. Fish, Lena M. Napolitano, Robert G. Sawyer, Douglas Slain, James P. Steinberg and Robert A. Weinstein. Clinical practice guidelines for antimicrobial prophylaxis in surgery.

Chopra T, Zhao JJ, Alangaden G, Wood MH, Kaye KS. Preventing surgical site infections after bariatric surgery: value of perioperative antibiotic regimen. Expert Rev Pharmacoecon Outcomes 2010;10: 317-27.

Aufenacker TJ, Koelemay MJW, Gouma DJ, Simons MP. Systematic review and meta-analysis of the effectiveness of antibiotic prophylaxis in prevention of wound infection after mesh repair of abdominal wall hernia. Br J Surg 2006; 93: 5-10.

Gravante G, Venditi D, Fillingeri V. The role of single-shot antibiotic prophylaxis in inguinal hernia repair. Annals of Surgery 2008; 248: 496-7.

Sanchez-Manuel FJ, Lozano-García J, Seco-Gil JL. Antibiotic prophylaxis for hernia repair.. Cochrane Database of Systematic Reviews 2007, Issue 3. Art. No.: CD003769. DOI: 10.1002/14651858.CD003769.pub3.

Abramov D, Jeroukhimov I, Yinnon AM, Abramov Y, Avissar E, Jerasy Z et al. Antibiotic prophylaxis in umbilical and incisional hernia repair: a prospective randomised study. Eur J Surg 1996; 162: 945–948.

Rios A, Rodriguez JM, Munitiz V, Alcaraz P, Perez Flores D, Parrilla P. Antibiotic prophylaxis in incisional hernia repair using a prosthesis. Hernia 2001; 5: 148–152.

Published
2014-11-03
How to Cite
1.
Pintar T, Trotovšek B, Beović B. Guidelines for antibiotic prophylaxis in abdominal surgery for adults. ZdravVestn [Internet]. 3Nov.2014 [cited 30Mar.2020];83(10). Available from: https://vestnik.szd.si/index.php/ZdravVest/article/view/1127
Section
Quality and safety