The management of highly pathogenic influenza h5n1 virus with possible interhuman transmission
Keywords:
highly pathogenic avian influenza, control measures, health care facilities, food safetyAbstract
Background: Avian influenza is an infectious disease of birds caused by A strain of the influenza virus. Some strains are highly contagious causing rapidly a fatal disease in poultry. The strains are known as HPAI (highly pathogenic avian influenza). Until year 1997, direct transmission of HPAI to humans was not known. During the last large outbreak of HPAI H5N1 in South-East Asia in 2004, the virus was transmitted to relatively low number of humans with a high mortality rate. The measures were taken to contain the outbreak of HPAI H5N1 in South-East Asia. However, there is a possibility that the disease might spread to other parts of the world. There is also a certain degree of concern regarding more intensified spread from birds to humans and frequent interhuman transmission.
Conclusions: In our paper, we present the recommended infectious control precautions in health care facilities with possible or confirmed case of HPAI H5N1, control measures in case of outbreak of HPAI in poultry in Slovenia and recommendations for travellers to the affected areas.
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References
Ito T, Kawaoka Y. Avian influenza. In: Nicolson KG, Webster RG, Hay AJ eds. Texbook of influenza. London: Blackwell Science; 1998. p. 126–37.
Suarez DL, Spackman E, Senne DA, Bulaga L, Welsch AC, Froberg K. The effect of various disinfectants on detection of avian influenza virus by real time RT-PCR. Av Dis 2003; 47: 1091–5.
Presečki V. Orthomyxoviridae. In: Presečki V, Mlinarić-Galinović G, PundaPolić V, Lukić A eds. Virologija. Zagreb: Medicinska naklada; 2002. p. 196– 7.
Yuen KY, Chan PK, Peiris M, Tsang DN, Que TL, Shortridge KF, Cheung PT et al. Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus. Lancet 1998; 351: 467–71.
Hien TT, Liem NT, Dung NT, San TL, Mai PP, Chau NV. Avian influenza A (H5N1) in 10 patients in Vietnam. N Engl J Med 2004; 350: 1179–88.
Anon. Avian influenza A (H5N1) in humans and poultry, Vietnam. Weekly Epidemiol Rec 2004; 79: 13–4.
Webby RJ, Webster RG. Are we ready for pandemic influenza? Science 2003; 302: 1519–22.
Katz JM, Lim W, Bridges CB, Rowe T et al. Antibody response in individuals infected with avian influenza (H5N1) viruses and detection of anti-H5 antibody among houshold and social contacts. J Infect Dis 1999; 6: 1763–70.
Buxton Bridges C, Katz JM, Seto WH et al. Risk of influenza A (H5N1) infection among health care workers exposed to patients with influenza A (H5N1), Hong Kong. J Infect Dis 2000; 1: 344–8.
Koopmans M, Wilbrink B, Conyn M, Natrop G, van der Nat H, Vennema H, Meijer A et al. Transmission of H7N7 avian influenza A virus to human beings during a large outbreak in commercial poultry farms in the Netherlands. Lancet 2004; 363: 587–93.
Centres for Disease Control and Prevention. Advice for travelers: precautions for travel to countries reporting H5N1. http://www.cdc.gov/travel/ other/precautions_avian_flu_020604.htm
World Health Organisation. WHO interim recommendations for protection of persons involved in the mass slaugher of animals potentially infected with highly pathogenic avian influenza viruses. http://www.who.int/csr/ disease/avian_influenza/guidelines/interim_recommendations/en/
Centres for Disease Control and Prevention. Interim Guidance for protection of persons involved in U. S. avian influenza outbreak disease control and eradication. http://www.cdc.gov/flu/avian/protectionguid.htm
World Health Organisation. Avian influenza A (H5N1). Weekly Epidemiol Rec 2004; 79: 41–2.
World Health Organisation. Avian influenza A (H5N1). Weekly Epidemiol Rec 2004; 79: 65–70.
World Health Organisation WHO Guidelines for Global Surveillance of Influenza A/H5. http://www.who.int/csr/disease/avian_influenza/guidelines/ globalsurveillance/en/
World Health Organisation. Interim protocol for public health management of possible/confirmed cases of avian influenza, 4 February 2004. http:// www.health.gov.au/avian_influenza/protocol.htm
World Health Organisation. Influenza A (H5N1). WHO Interim Infection Control Guidelines for Health Care Facilities. http://www.who.int/csr/ disease/avian_influenza/guidelines/infectioncontrol1/en/
Centres for Disease Control and Prevention. Interim recommendations for infection control in health-care facilities caring for patients with known or suspected avian influenza. http://www.cdc.gov/flu
Lužnik-Bufon T, Škerl M. Strokovne podlage za pripravo programa za obvladovanje in preprečevanje bolnišničnih okužb: 2000–2003. Ljubljana: Slovensko zdravniško društvo, Sekcija za klinično mikrobiologijo in hospitalne infekcije; 2003.
Advisory Committee on Immunization Practices. Prevention and control of influenza. MMWR 2003; 52: 1–36.
Leneva IA, Roberts N, Govorkova EA, Goloubeva OG, Webster R. The neuraminidase inhibitor GS4104 (oseltamivir phosphate) is efficacious against A/Hong Kong/156/97 (H5N1) and A/Hong Kong/1074/99 (H9N2) influenza viruses. Antiviral Res 2000; 48: 101–15.
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