PREVALENCE OF HEPATITIS A IN B AMONG BLOOD DONORS WITH HISTORY OF JAUNDICE
DOI:
https://doi.org/10.6016/ZdravVestn.2287Keywords:
blood donors, questionnaire, jaundice, hepatitis A, BAbstract
Background. Preventing transmission of infectious disease through blood transfusion presents one of the greatest challenges of transfusion medicine. All donations are monitored for syphilis since 1960, hepatitis B (HBsAg) since 1970, aids (anti HIV) since 1986 and hepatitis C (anti-HCV) since 1993.
After introducing a donor questionnaire in 1994, we started to test all donors with a history of hepatitis for anti-HBc, antiHBs antibodies, and antibodies against hepatitis A (anti-HAV).
Methods. Data on donors were found in the Datec computer program which is commonly used in all transfusion institutions in Slovenia.
Results. Among 43,000 registered donors, 764 (1.78%) had a history of hepatitis. After testing, we found 666 of them positive (87.2%) for hepatitis A or B antibodies. 654 (85.6%) donors had hepatitis A antibodies and 98 (12.8%) had anti-HBc antibodies. Among these 98, 30 donors (30.6%) had no anti-HBs antibodies. 86 donors (11%) had antibodies against hepatitis A and B.
Conclusions. After additional testing of donors for hepatitis B antibodies, we excluded 30 (0.069%) HBsAg negative, antiHBc positive and anti-HBs negative donors with history of hepatitis.
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