Arterial compliance measurements in Slovenian children and adolescents
DOI:
https://doi.org/10.6016/ZdravVestn.3036Keywords:
child, reference range, blood pressure, arterial stiffness, applanation tonometryAbstract
Background: In recent years, the occurrence of cardiovascular risk factors in Slovenian children has been increasing. Pulse wave velocity (PWV) measurement is a noninvasive technique that could contribute to assessing cardiovascular disease risk in healthy children for preventive purposes. The aim of this pilot study is to gain reference values for PWV in children, with the purpose of long-term assessment of cardiovascular risk.
Methods: Between April 2018 and June 2019, PWV measurements were performed in 150 children from elementary schools and high-school students in the Maribor area. Every age group consisted of children without associated diseases that could have an impact on PWV. The percentile diagram was outlined with LMS methodology and the curves defined with the function based on “BCCGo” distribution.
Results: We have confirmed that PWV values rise with age (rho = 0.387; p < 0.001). Based on the information gathered, we used the LMS method to calculate percentile values of PWV according to age with graphic presentation. Comparing PWV values, we found that they differ statistically (H = 23.062; p < 0.001). We also found out that the ratio between systolic and diastolic blood pressure weakly negatively correlates with PWV (rho values = -0.218; p = 0.043).
Conclusions: In this pilot study, preliminary age-dependent paediatric reference values of PWV were determined, and the usefulness of the method for preventive purposes due to its non-invasiveness and simplicity was confirmed. Although the results are promising, testing on a larger sample of subjects is necessary with the aim of defining national reference values and using this method in monitoring the cardiovascular health of the Slovenian paediatric population.
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