LUNG FUNCTION TESTING IN CHILDREN

Authors

  • Matjaž Fležar Klinični oddelek za pljučne bolezni in alergijo Bolnišnica Golnik 4204 Golnik

Keywords:

spirometry, bronchial provocation testing, metacholine

Abstract

Background. Lung function testing in children above five years old is standardised similarly as is in adult population (1). Nevertheless bronchial provocation testing can be more hazardous since the calibre and reactivity of childhood airway is different. We analysed the frequency of different lung function testing procedures and addressed the safety issues of bronchial provocation testing in children.

Methods. We analysed lung function testing results in 517 children, older than 5 years, tested in our laboratory in threeyear period. Spirometry was done in every patient, metacholine provocation test was used as a part of diagnostic work-up in suspected asthma. In case of airway obstruction, bronchodilator test with salbutamol was used instead of a metacholine provocation test.

Results. The most common procedure in children was spirometry with bronchial provocation test as a part of diagnostic work-up of obstructive syndrome (mostly asthma). 291 children required metacholine test and 153 tests were interpreted as positive. The decline in expiratory flows (forced expiratory flow in first second – FEV1) in positive tests was greater than in adult population as was the dose of metacholine, needed to induce bronchoconstriction. The compliance of children was better than in adults.

Conclusions. Lung function testing in children is reliable and safe and can be done in a well-standardised laboratory that follows the regulations of such testing in adults.

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References

Quanjer PhD, Tammeling GJ, Cotes JE. Eur Respir J 1993; 6: Suppl 16: 5–40.

Sekulić S, Slavković V, Veljković V, Vučo J. Normal values of vital capacity and maximum expiratory volume per second in children 7 to 18 years of age. Tuberkuloza 1968; 20: 142–9.

Hargreave FE, Ryan G, Thomson NC, O’Byrne PM, Latimer K, Juniper EF, Dolovich J. Bronchial responsiveness to histamine or methacholine in asthma. Measurement and clinical significance. J Allergy Clin Immunol 1981; 68: 347–55.

Fležar M, Šorli J, Kandare F, Šuškovič S. Standardizacija bronhialnega provokacijskega testa z metaholinom. Zdrav Vestn 1997; 66: 261–2.

Kiviloog J. The correlation between exercise-induced bronchoconstriction and bronchial methacholine sensitivity in asthma. Pediatrics 1975; 56: 908– 9.

Quanjer PhD, Helms P, Bjure J. Eur Respir J 1993; 6: Suppl 16: 5–40.

Crapo RO, Casaburi R, Coates AL. Guidelines for methacholine and exercise challenge testing 1999. Am J Respir Crit Care Med 2000; 161: 309–29.

Wanger J. Quality assurance. Respir Care Clin N Am 1997; 3: 273–89.

Issue

Section

Professional Article

How to Cite

1.
LUNG FUNCTION TESTING IN CHILDREN. ZdravVestn [Internet]. 2004 Mar. 13 [cited 2024 Nov. 2];73(3). Available from: https://vestnik.szd.si/index.php/ZdravVest/article/view/2264

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